After intramuscular injection in the buttocks, there is a numbness in one area of the buttocks, it is possible that there is an adverse reaction after intramuscular injection. Because some drugs may have an irritating effect on muscles and soft tissues, after intramuscular injection, patients may have local pain, subcutaneous hardness or numbness of the skin. In addition, in the process of injection, if you do not pay attention to the operation specification, damage to the sciatic nerve or the liquid on the sciatic nerve stimulation, may also appear local numbness symptoms. In this case, first of all, we should pay attention to rest, continue to observe, you can make appropriate hot compresses on the local area to promote blood circulation and improve the symptoms of numbness, you can also use nutritive nerve medication, such as the application of methylcobalamin tablets and other medications to treat and relieve the symptoms. If the patient also accompanied by other symptoms, also need to go to the hospital for further examination, in order to clarify the diagnosis, and according to the cause of targeted treatment.