Splenectomy eliminates the phagocytosis of red blood cells by the spleen, etc. Indications include traumatic splenic rupture, hypersplenism, and hematopoietic disorders.
In hypersplenism, the residence time of intra-splenic blood flow in the spleen is increased, and the phagocytosis function of macrophages is enhanced, phagocytosing a large number of blood cells, leading to a decrease in white blood cells, platelets and red blood cells in the peripheral blood. After performing splenectomy, the decrease in blood counts can be suppressed.
After traumatic splenic rupture, if the spleen is severely ruptured, it may cause massive blood loss or even shock, at which time the spleen needs to be removed in order to save life.
Certain diseases of the hematopoietic system, such as hereditary spherocytosis and elliptical erythropoiesis, in which the red blood cells are extremely easy to be destroyed by the spleen, can cause severe anemia and jaundice. Removal of the spleen can curb the destruction of red blood cells and improve the condition.