Sleep holding breath and waking up may be due to mental factors, bronchial asthma, pneumonia, sleep apnea syndrome, acute left heart failure and other reasons. 1. Psychological factors: mental tension, anxiety, depression during the day, leading to autonomic nerve disorders, so sleep holding breath, waking up. 2. Bronchial asthma: when sleeping at night, acute attack of bronchial asthma can lead to breathlessness and waking up during sleep. 3. Pneumonia: Inflammation of the lungs, causing coughing, sputum, dyspnea, shortness of breath, so that when you sleep, breathlessness, wake up. 4. Respiratory sleep apnea syndrome: because of the obstruction of the airway leads to breathlessness, so when sleeping, breathlessness, waking up, can be seen in adenoid hypertrophy and so on. 5. Acute left heart failure: increase in the volume of return blood at night, the heart can not withstand too much return blood volume and lead to breathlessness, so hold your breath and wake up. Sleeping breathlessness may also have other causes, it is recommended to consult a doctor in time to identify the cause of the disease, early treatment.