Peptic ulcers mainly refer to chronic ulcers that occur in the stomach and duodenum, and gastric ulcers refer to chronic ulcers that occur in the stomach, so the difference between the two is that the ulcers occur in different areas. Peptic ulcers include gastric ulcers and also duodenal ulcers, such as duodenal bulb ulcers, duodenal descending ulcers, transverse ulcers, etc. Gastric ulcers refer to fundic ulcers, horn ulcers, sinus ulcers, and gastric body ulcers. Regardless of the type of peptic ulcer, it will clinically manifest as regular epigastric pain with abdominal distension, nausea, vomiting, acid reflux, and loss of appetite. There is also no difference in treatment between the two, which are mainly treated with acid-suppressing drugs combined with gastric mucosal protective agents. If H. pylori infection is present, H. pylori eradication therapy needs to be given.