HFMD is an acute infectious disease caused by a variety of enterovirus infections, mostly in preschool children, with the highest incidence in children under 3 years of age. The main manifestations are papular rash and herpes on the hands, feet, mouth and buttocks, with or without fever. In a few cases, encephalitis, meningitis, encephalomyelitis, and in severe cases, brainstem encephalitis causing pulmonary edema and pulmonary hemorrhage, which can lead to death if not treated in time. A. What are the symptoms of hand, foot and mouth disease? The main symptoms of HFMD are rash and fever, which can be followed by fever or rash followed by fever. The rash mainly appears on the oral mucosa, hands, feet and buttocks, and is a scattered red papule and herpes. The rash usually appears first in the oral cavity as red papules or multiple ulcers, mainly on the palate; then the rash appears on the hands and feet and buttocks. In some cases, the rash appears only in the mouth or on one or two parts of the hands, feet, or buttocks. The rash is not painful or itchy. In severe cases with neurological involvement, poor mental health and drowsiness, easily startled, irritable, crying and restlessness, headache, nausea, vomiting, shock-like trembling of the limbs, weakness, unstable walking or paralysis may occur. In critical cases, the disease progresses rapidly and can suddenly appear coma, respiratory distress, purple lips, cold hands and feet, cold sweat, pulmonary hemorrhage, and death by shock Second, how should a child with HFMD seek medical attention? 1. If a child with mild illness has only a rash, no fever or transient fever, no other symptoms, good spirit, can eat and play, he can be isolated and observed at home. 2, children with one of the following conditions should immediately go to the designated hospital for hand, foot and mouth disease: ① under 3 years old. ② persistent fever. ③Poor mental health and drowsiness. ④Easy to be frightened, easily irritated, crying and restless. (⑤) Shock-like trembling of limbs, weakness, unstable walking or paralysis. (6) Headache, nausea, vomiting. (7) Recurrent transient erythema on the face, neck, chest and back. (8) Cold hands and feet, cold sweat. 3. Some children with no rash should be seen immediately at a hospital above the county level if they have one of the following manifestations during the HFMD epidemic season: ① Fever of unknown origin. ② Vomiting and diarrhea without obvious reasons. ③Crying, frightening and irritable for no apparent reason. (④) shaking, twitching and weakness of limbs without obvious reasons. 3. What is the effect of treatment of HFMD? Most children with mild disease can be cured without treatment and have a good prognosis. Most children with severe disease can recover successfully without sequelae as long as they are treated promptly. Those with severe neurological damage may have different degrees of functional impairment such as mental retardation and limb paralysis. Very few cases progress rapidly, with pulmonary hemorrhage and shock, and death is too late or the treatment is ineffective. Fourth, how is HFMD transmitted? Hand, foot and mouth disease patients and hidden infected people are the source of infection, mainly through the gastrointestinal tract, respiratory tract and close contact and other means of transmission. In order to prevent the transmission of children with HFMD, parents should do the following: wash hands and change clothes; drink boiled water and eat cooked food; eat fresh fruits and wash them clean; wash milk utensils and toys regularly; clean and ventilate the room regularly; reduce the number of children going out, especially in crowded public places; wash hands and change clothes before coming into contact with children after parents return home.