Closed-cell acne can be treated with medications, such as retinoids, or with chemical peels. Closed mouth acne is a mild form of acne and is treated with topical medications, commonly used medications are retinoids, including adapalene gel and retinoid ointment. Closed-cell acne can also be removed by chemical peeling. Fruit acids and salicylic acid are commonly used in chemical peeling, which can accelerate the shedding and renewal of epidermal cells. In addition, you can also use an acne squeezer to squeeze out the material inside the acne. It is important to keep the skin clean and avoid scratching and squeezing acne. If closed mouth acne occurs, you should go to the hospital in time for examination, and the use of the above medication should be in accordance with the doctor’s instructions.