Hot flashes and night sweats are common symptoms of tuberculosis and hyperthyroidism, and treatment should pay attention to identifying and treating the original cause to avoid misdiagnosis. In general, when sweating occurs, first consider the temperature, clothing and other reasons, and then consider whether it is pathological if physiological factors are excluded. Due to hyperthyroidism, excessive secretion of thyroxine and increased metabolic rate can lead to fear of heat and excessive sweating, and hyperthyroidism tests to detect hyperthyroidism and laboratory tests to check the level of thyroid hormones in the blood. The main cause of excessive sweating in diabetic patients is plant nerve dysfunction, sympathetic excitation, and increased sweat gland secretion, which can be detected by testing blood sugar, in general. Generally when fasting whole blood glucose ≥ 6.7 mmol/L (120 mg/dL) and plasma glucose ≥ 7.8 mmol/L (140 mg/dL), 2 repeated determinations can be diagnosed as diabetes mellitus. Hot flashes and night sweats are one of the symptoms of tuberculosis intoxication, which is the result of the stimulation of the central nervous system by the toxins of the tubercle bacilli and their metabolites, leading to dysfunction of the autonomic nervous system, and can be diagnosed by the tuberculin test. Tidal sweating is also one of the common symptoms of tumor patients. In addition, hypertension, menopausal syndrome, hypoglycemia, systemic lupus erythematosus, endocarditis and other diseases as well as postoperative physical weakness, mental stress and psychological pressure may cause tidal sweating. However, most of the sweating is caused by plant nerve dysfunction, and its pathogenesis is mainly due to abnormal excitation of sympathetic nerves.