Ozagrel and butylphthalide can be used together. 1. Ozagrel: belongs to the thromboxane-activating enzyme inhibitor, can inhibit the generation of TXA2 after use, and thus has the effect of anti-platelet aggregation as well as vasodilatation, and is mainly used in the treatment of acute thrombotic cerebral infarction, cerebral infarction accompanied by movement disorders and other diseases. Nausea, vomiting, urticaria and other discomforts may occur after the use of the drug. The drug is contraindicated in people who are allergic to the components of the drug, severe cardiac arrhythmia, severe hypertension. Avoid mixing with calcium-containing infusion during the course of medication, while pregnant and lactating women need to use the drug under the guidance of a doctor. 2. Butylphthalide: after the use of the central nervous function of the damage has improved, but also has a relatively strong anti-ischemic effect, but also inhibit neuronal apoptosis, and has anti-thrombosis and anti-platelet aggregation effect. It is mainly used for the improvement of the treatment of neurological deficits in acute ischemic stroke. Usually the drug may cause diarrhea, elevated blood sugar, chest tightness and other discomforts after use. And it is forbidden for those who are allergic to the components of the drug. During the use of the drug, it is necessary to pay attention to bradycardia, hepatic impairment, severe bleeding and so on. And pregnant and lactating women need to use the drug under medical supervision. Butolphthalein and Ozagrel can be used together without contraindications, and can achieve the effect of improving blood circulation in the brain. However, it is important to note that all the above drugs should be used under the guidance of a doctor.