The drugs used in the secondary prevention of lacunar cerebral infarction mainly include antihypertensive drugs, lipid regulating drugs, hypoglycemic drugs, antiplatelet drugs and so on. 1. Antihypertensive drugs: hypertension is a common risk factor for lacunar cerebral infarction. Antihypertensive drugs mainly include metoprolol, captopril, amlodipine, etc., which can reduce the risk of infarction through the regulation of blood pressure. 2. Lipid-regulating drugs: those with hyperlipidemia should apply lipid-regulating drugs such as atorvastatin calcium appropriately. 3. Hypoglycemic drugs: diabetes mellitus is also a risk factor for cerebral infarction, and attention should be paid to the regulation of blood glucose, commonly used hypoglycemic drugs include metformin, rosiglitazone and so on. 4. Antiplatelet drugs: such as aspirin, clopidogrel, etc., to prevent platelet aggregation and thrombosis leading to cerebral infarction. All drugs should be used in accordance with medical advice.