Taking medicine feels blocked in the chest and back pain should be treated according to different causes, which mainly include oversized tablets, esophageal stenosis, esophageal spasm during swallowing and so on. 1. Pill is too big: pill is too big in the process of taking medication may be stuck in the esophagus, and the drug ingredients will produce a certain amount of stimulation of the esophagus, which will appear chest discomfort, back pain, this situation does not need to carry out special treatment, you can use some water to promote the amount of drugs into the stomach. 2. Esophageal stenosis: If there is esophageal stenosis, there may be difficulty in swallowing, so there will be the situation of getting stuck when taking medicine, and there will be pain when swallowing tablets, this situation needs to go to the hospital, and can be treated with drugs such as trimethoprim injection and mitomycin injection. 3. Esophageal spasm during swallowing: most of the esophageal spasm is caused by esophageal dysfunction, the clinical manifestation is chest pain, dysphagia and other symptoms, if the esophageal spasm occurs when taking medicines, it will lead to the situation of getting stuck in the medicines and chest pain, which can be treated by the medicines such as pivivoxyl bromide tablets, otipecotic bromide tablets, trametine maleate tablets and other medicines. It is recommended to go to the hospital for examination to find out the cause and timely symptomatic treatment.