Headache and fear of cold is not a brain tumor, it may be related to migraine attack during women’s menstruation, or it may be related to meningitis, encephalitis and other diseases. 1. Migraine: During female menstruation, due to the change of hormone level in the body, it may lead to the occurrence of migraine, when the patient will have the symptoms of headache and fear of cold, but these are the symptoms caused by the two reasons respectively, the headache is caused by the migraine, and the fear of cold is the normal performance in the menstruation period. 2. Meningitis: patients with meningitis may have headache and chills, often accompanied by fever, nausea and vomiting, impaired consciousness, generalized weakness and other symptoms. 3. Encephalitis: patients with encephalitis may also have headache and fear of cold, in addition to fever, drowsiness, lethargy, coma, nausea and vomiting, irregular respiratory rhythms, pupil irregularity and other symptoms. In addition to the above factors, acute upper respiratory tract infections and other diseases can also cause headache and chills, if these symptoms continue to be unrelieved, please consult a doctor in time to avoid delaying the condition.