Short intervals between antihypertensive drugs may affect the therapeutic effect of the drug, there may also be adverse reactions to the drug, it is recommended to strictly follow the doctor’s instructions to standardize the use of drugs. The dosage time of antihypertensive drugs is related to the patient’s physical condition and the half-life of the drug, if the interval is too short, the phenomenon of drug overdose may occur, which not only fails to achieve the therapeutic effect, but also causes abnormal fluctuations in blood pressure. If the interval between antihypertensive drugs is too short, the body can not be fully metabolized, which may cause damage to the liver and kidney function, and also increase the incidence of adverse reactions such as dizziness, nausea, abdominal pain, skin rash. Therefore, it is recommended that patients use antihypertensive drugs in accordance with their own conditions under the guidance of a doctor, do not take them without authorization, and consult a doctor in case of discomfort.