Nifurtimox itching after use may be inflammation or drug stimulation, allergies, if it is mild itching can continue to use the drug, if the itching symptoms are serious can not continue to use, need to stop using the drug in a timely manner. Nifurtimox is a topical vaginal medication used for the treatment of vaginal inflammation caused by bacteria, trichomonas, and Pseudomonas vulvovaginalis infections. The use of the drug may irritate the vaginal mucosa with itching symptoms, or the inflammation itself can also cause itching, and is not caused by the use of the drug. If the itching is not serious, you can use warm water to wash the vulva localization after continuing to use the drug observation, treatment is strictly prohibited during the period of coitus stimulation. If the vaginal or vulvar itching is worse than before after using Nifurtimox, it may be related to drug allergy, or even local redness, swelling or pain and other symptoms. In this case, you need to stop using the drug, use warm water to wash the vulva and vagina, and suggest taking loratadine, chlorpheniramine maleate tablets and other drugs as prescribed by the doctor for anti-allergy treatment. When itching occurs after using Nifurtimox, pay attention to vulvar hygiene, consult a doctor to check the cause of itching, and decide whether to continue using the drug under the guidance of the doctor.