Whether or not bile reflux is serious after cholecystectomy should be determined on a case-by-case basis. It is more common for patients to develop bile reflux because they do not have the ability to store bile after surgery. 1. Mild bile reflux: Due to the removal of the gallbladder, the patient loses the ability to contract and store bile. Patients will experience abdominal pain and indigestion, and often return to normal 2-3 months after the operation, usually without special treatment. 2. Severe bile reflux or unrelieved bile reflux: If the bile reflux is more serious after surgery, the alkaline bile affects the acidic environment of the stomach, and other complications such as esophagitis and bile reflux gastritis may occur, which need timely treatment to relieve the discomfort caused by bile reflux. Patients with bile reflux after cholecystectomy should go to the hospital for timely treatment if the symptoms are severe to avoid aggravation of the condition.