Antihypertensive drugs that can cause bradycardia are mainly beta-blockers, representative drugs are metoprolol, bisoprolol, etc. If the patient’s heart rate is usually slow, try not to apply this kind of drug, this kind of drug is mainly applicable to patients with high blood pressure combined with fast heart rate. Nifedipine tablets and other drugs may lead to reflex heart rate increase due to the lowering of blood pressure. If the patient’s heart rate is slow, calcium channel antagonists, such as nifedipine, baisin et al, can be applied appropriately. If the patient has cardiovascular disease or combined with renal insufficiency, within the range of application, the patient can appropriately apply ARBs such as irbesartan and valsartan to reduce blood pressure, while improving the prognosis of target organs.