Rough face with lots of small granules may be due to diseases such as urticaria, keratosis pilaris, and hidradenitis suppurativa. 1. Urticaria: It is usually considered to be related to food and drug allergies, infections, systemic diseases, physical and other factors. There are more types of the disease, and most patients often have localized windburn, angioedema and other symptoms, similar to the orange peel-like appearance, which can be manifested as a lot of small particles on the face roughness. Some patients can also be accompanied by fever, nausea, abdominal pain, chest tightness and other systemic symptoms. 2. Keratosis pilaris: the cause of the disease is not clear, and it is considered to be related to heredity, vitamin deficiency, metabolic disorders and other factors, and the existence of endocrine diseases, glucocorticoid therapy, etc., which can also induce keratosis pilaris. Patients often present with normal-skinned or reddish papules with a chicken-skin appearance, which may also appear as roughness on the face with many small granules. Some patients may also have mild itching symptoms. 3. Sweat duct tumor: the cause of the disease is still unclear, and it is mostly considered to be related to heredity, mental abnormality, Down’s syndrome, endocrine and other factors. Patients often do not have self-conscious symptoms, mostly manifested as normal skin color, yellowish, brownish hemispherical lesions or flat papules, can also appear rough face with a lot of small particles. In addition to the above, flat warts, whiteheads and other acne can also be manifested in the face rough with a lot of small particles. It is recommended that patients with rough face with a lot of small particles, actively consult a doctor to cooperate with the examination, and follow the doctor’s instructions for reasonable treatment.