GERD, or gastroesophageal reflux disease, is a functional disease that refers to the clinical manifestations and pathological changes caused by the reflux of gastroduodenal contents into the esophagus. It can be divided into endoscopically negative and endoscopically positive, that is to say, with GERD symptoms, after gastroscopy, whether the lesion site can be found. If it is positive, it is also known as esophagitis. Depending on the reflux material, it can also be divided into gastroesophageal reflux and gastroduodenoesophageal reflux; or acid reflux and alkaline reflux: 1, medication is not effective, or the patient does not want to use medication for a long time; 2, with more serious extraesophageal symptoms, such as chronic cough, asthma, otitis media, etc.; 3, type I esophageal hiatal hernia, medication is not effective or the patient does not want to use medication for a long time; 4, type II, type III esophageal hiatal hernia; 5, severe reflux esophagitis, or with precancerous lesions such as Barret’s esophagus.