The normal value of fibrinogen is 2-4 g/L, so exceeding 4 g/L is a relatively dangerous situation. Fibrinogen is closely related to cardiovascular disease, especially in patients with elevated fibrinogen, who have a higher rate of death from myocardial infarction. The degree of risk is also greater if fibrinogen is significantly elevated. Fibrinogen can promote the aggregation of platelets in the blood, including the growth, proliferation and contraction of smooth muscle as well as endothelial cells, thus increasing blood viscosity and peripheral resistance, which can cause endothelial cell damage and easily result in red blood cell adhesion and thrombus formation, thus fibrinogen is closely related to the development of cardiovascular diseases. In particular, atherosclerosis, due to elevated fibrinogen and platelet accumulation capacity in a hypercoagulable state, is more likely to lead to cardiovascular accidents if combined with other predisposing cardiovascular disease factors. In addition it is also an important factor in triggering and aggravating hypertension. Fibrinogen elevation should go to identify its causes, timely dietary modifications, smoking and alcohol cessation, and treatment of the corresponding diseases.