The blisters rubbed out on the legs are usually due to the accumulation of tissue fluid caused by local friction for a long time. If the blisters are small, they can be left to naturally absorb, crust and fall off: if the blisters are large, they need to go to the hospital in time, have the pus aseptically drained out by the doctor, and then be bandaged. Smaller blisters on the feet, generally do not need special treatment, generally reduce foot movement, change suitable shoes or wear more pairs of socks to reduce friction can be. If the local skin, in addition to pain, is accompanied by an increase in skin temperature, blisters are large, it is recommended to go to the hospital for disinfection, extraction of blisters, bandaging and other treatments, so as not to cause infection due to improper treatment of wounds, to avoid pus breakthrough of the wound. It is recommended that patients usually pay attention to wearing appropriate clothing or shoes to avoid friction and irritation. If the condition is serious, the patient should consult a doctor in time and follow the doctor’s instructions.