Long-acting antihypertensive drugs are generally maintained for 24 hours, and will not be able to maintain only 4~5 hours. 1. Long-acting antihypertensive drugs maintain their effects for a longer period of time and are relatively slow to take effect. Clinical long-acting antihypertensive drugs can maintain 24 hours, such as fosinopril sodium, enalapril maleate tablets, benadryl hydrochloride, timosartan, valsartan and other medications, and won’t only last 4 to 5 hours. 2. Maintain 4~5 hours of antihypertensive drugs are considered to be short-acting antihypertensive drugs, short-acting antihypertensive drugs generally maintain 5~8 hours, such as nifedipine to maintain about 5 hours, captopril to maintain about 6 hours, short-acting antihypertensive drugs have a relatively fast onset of action, but the maintenance time is relatively short. Hypertensive patients in the clinical application of antihypertensive drugs, most of them can maintain 24 hours, for can not maintain 24 hours of antihypertensive drugs, the use of time to take according to the amount, so as not to lead to blood pressure control is not stable. Specific medication need to follow the doctor’s instructions, do not self-medication.