Esophagitis may be reflux esophagitis, infectious esophagitis, eosinophilic esophagitis and so on. Depending on the cause of the disease, drugs such as omeprazole, aluminum thioglycollate, domperidone, fluticasone propionate, fluconazole, etc. can be chosen to cure the disease. 1. Reflux esophagitis (1) Proton pump inhibitor (PPI) drugs: PPI is the first choice for the treatment of reflux esophagitis, a single dose of PPI treatment is ineffective can be changed to double the dose, a PPI is ineffective can try to switch to another PPI. commonly used PPIs are omeprazole, epprazole and so on. (2) Gastric mucosal protective agent: it can enhance the defense ability of gastric mucosa, and it is suitable for those who have gastric mucosal erosion, bleeding or obvious symptoms. Aluminum thioglycollate, magnesium aluminum carbonate, etc. can be used. (3) Promoting the power of the drug: applicable to the epigastric fullness, early satiety as the main symptoms. Commonly used drugs are domperidone, itopride, mosapride and so on. 2. Eosinophilic esophagitis is usually treated with hormonal drugs, such as fluticasone propionate, prednisone and so on. 3. Fungal infectious esophagitis: antifungal drugs such as fluconazole can be used. It is recommended that patients go to the hospital for gastroscopy to further clarify the cause of the disease, and follow the doctor’s instructions for targeted drug therapy.