A high risk does not necessarily mean that there is a problem. Ultrasound is the gold standard for the diagnosis of open neural tube defects. The ultrasound examination can be completed in a tertiary hospital with good medical conditions, and the fetal cranial and spinal conditions can be systematically evaluated to determine whether the pregnancy can be continued or terminated. 1. Continuing the pregnancy: Go to a local tertiary hospital with good medical conditions and improve the ultrasound examination under the examination of an experienced doctor. If there is no indication of fetal neural tube defects, which will not affect the development of the fetus, the pregnancy can be continued, and at the same time, regular checkups can be conducted to observe the development of the fetus. 2. Termination of pregnancy: If it is clear from the ultrasound examination that the fetus has open neural tube defects, such as anencephaly and spina bifida, it is recommended to terminate the pregnancy in time. If the ultrasound examination shows that the fetus has open neural tube defects, it is recommended to terminate the pregnancy promptly. If the test report suggests a high risk of open neural tube defects, it is recommended to consult the hospital in a timely manner, further improve the examination according to the situation of the pregnancy, and deal with it under the guidance of the doctor, do not be too anxious.