Cocaine should be used with attention to the use of timing, use, and so on. 1. Timing: the use of corkscrew should first master the timing, corkscrew is mainly used to treat constipation drugs, can stimulate lubrication of the intestinal wall, soften the stool, etc., need to wait until the stool into the anus for use, if the stool is not to the anus, on the use of corkscrew, at this time and can not play a very good role. 2. Use: Corkscrew should be used to remove the cap of the bottle, slowly inserted into the anus, at this time should pay attention to the mouth of the bottle of Corkscrew is smooth and no thorns, Corkscrew bottle hard, such as sharp thorns are easy to scratch the tissues in the anus, which will cause bleeding and other symptoms, may cause secondary infections. Corkscrew adverse symptoms are still unclear, if the patient is allergic to Corkscrew, should not be used; Corkscrew traits change should not be used, the patient is best to use under the guidance of a professional doctor.