1. Antibiotics Taking cephalosporins, sulfonamides, nitromidazole antibiotics at the same time drinking alcohol, there will be the so-called “disulfiram-like reaction”, that is, the accumulation of alcohol metabolites acetaldehyde in the body. It usually occurs within 15-30 minutes after taking the medication and drinking alcohol, and is characterized by facial flushing, conjunctival congestion, headache, dizziness, nausea, vomiting, sweating, chest pain and other symptoms, leading to myocardial infarction, acute heart failure, acute liver damage and even death. Sometimes eating chocolate with alcohol, taking patchouli, or even rubbing alcohol on the skin after taking the drug can cause mild disulfiram-like reactions. Drugs involved: antibiotics with the words “cephalosporin”, “nitrazole”, “sulfonamide”, “camptothecin”, etc. Alcohol itself has a paralyzing effect on the nerves, and when sedative-hypnotic drugs are taken, a synergistic effect will occur, aggravating the effect and toxicity of both, resulting in lethal poisoning, generally manifested as drowsiness, trance, coma, respiratory failure and even death. The danger occurs mostly during sleep, so it is difficult to be detected, and the famous comedian Chaplin passed away as a result. Drugs involved: sedative drugs with the words “Valium” and “diazepam”. 3. blood pressure drugs Several types of clinically used blood pressure drugs can have a synergistic effect with alcohol, some leading to a sudden rise in blood pressure, severe headaches, vomiting, palpitations and other symptoms, and even cerebral hemorrhage and death; some enhance the vasodilator effect of drugs, causing sudden hypotension, leading to fainting, falls and other accidents, and in serious cases, resulting in infarction due to insufficient blood perfusion in the brain, liver, kidneys and other important organs. Drugs involved: nifedipine, diclozapine, metoprolol and other types of blood pressure lowering drugs. 4. Hypoglycemic drugs Alcohol and hypoglycemic drugs will affect each other’s metabolism in the body and increase the risk of hypoglycemia, manifested as panic, sweating, fatigue and weakness, or even irritability, multitalking, confusion, etc., which are often ignored as drunkenness, and in serious cases, hypoglycemic shock or even death occurs. Drugs involved: metformin, gliclazide and injectable insulin and other hypoglycemic drugs. 5. Non-steroidal anti-inflammatory drugs Non-steroidal anti-inflammatory drugs and alcohol can stimulate the secretion of large amounts of gastric acid and destroy the gastric mucosal barrier, resulting in erosion, ulceration, and even gastric bleeding. It generally manifests as stomach pain, gastric distension, acid reflux, belching, vomiting blood, black stool, etc. In severe cases, hemorrhagic shock or even death occurs. Drugs involved: aspirin, fen-phen, diclofenac and other antipyretic and analgesic drugs, and cold medicines containing these ingredients. Reminder: All alcohol consumption is prohibited during medication, do not be embarrassed to refuse and drink alcohol during medication, which can not meet the pleasure of drinking among friends, but also on their own health, if too much socializing, try to drink alcohol a week after stopping medication, or taking Chinese medicine, consult your doctor when buying drugs, and learn in detail about the adverse effects of drugs and alcohol, so as not to bring health to yourself and your family! hidden dangers!