Bitter mouth, dry mouth, generalized weakness and fatigue may be caused by indigestion, diabetes, pharyngitis, etc. It can be treated by adjusting the diet, oral hypoglycemic drugs and anti-infective drugs. 1. Indigestion: If the patient likes to overeat for a long time, spicy and greasy stimulating food, it will make the food pile up in the body for a long time, resulting in indigestion, and the symptoms of bitter mouth and dryness and fatigue may occur. You can improve your diet by avoiding overeating, avoiding greasy food, and eating smaller meals. 2. Diabetes mellitus: Diabetes mellitus patients due to high blood sugar in the body, the sugar can not be utilized, which may have a bitter mouth and dryness of the body fatigue and tiredness of the symptoms. Oral hypoglycemic drugs, such as metformin hydrochloride tablets, gliclazide extended-release tablets, etc. for treatment, allergic to drug ingredients, severe renal and hepatic insufficiency is prohibited. 3. Pharyngolaryngitis: Pharyngolaryngitis may lead to decreased secretion function of the mucous membrane glands in the throat, decreased secretion, decreased resistance, which may lead to symptoms of bitter mouth and dryness, generalized weakness and fatigue. Patients can be treated by oral anti-infective drugs, such as amoxicillin capsules, cefaclor granules, etc., allergic to drug components are prohibited. When the patient appeared bitter mouth dry body fatigue fatigue symptoms, it is recommended to consult a doctor to identify the cause of the disease, follow the doctor’s instructions for medication, do not use drugs, so as not to aggravate the condition.