A painless, solitary hard lump in the breast is the clinical characteristic of fibroadenoma of the breast. Breast fibroadenoma is the most common benign breast tumor, which occurs mostly in young women. The lumps are mostly round, with smooth surface, clear demarcation with surrounding tissues and no adhesions. Breast tuberculosis is common in middle-aged women, with few systemic symptoms of tuberculosis, mainly manifested as breast lumps, with a slow course. After rupture, ulceration and long-lasting overflow may occur, and there is a thin pus like bean residue, and the ipsilateral axillary lymph nodes are often obviously enlarged. To prevent painless, solitary hard lumps in the breast, it is important to maintain a relaxed and emotionally stable mood. Emotional instability can inhibit the ovulatory function of the ovaries, resulting in a decrease in progesterone and a relative increase in estrogen, leading to breast lumps. Avoid using creams and medications that contain estrogen. Some women use estrogen-containing creams for a long time for skin beauty, which can induce breast enlargement in the long run. Pregnancy and breastfeeding are a physiological regulation of breast function, so marriage and breastfeeding at the right time are beneficial to the breast; on the contrary, women over 30 who are unmarried, have not had children or are breastfeeding are prone to breast problems. Treatment of painless, solitary hard lumps in the breast should first be based on early detection and diagnosis. Women should be alert to breast disease, a highly prevalent female disease, and should perform regular monthly self-examinations, preferably about 1 week after menstruation, when the breast is softer and lumps are easily palpable. When found, they should go to the hospital for a standardized examination as soon as possible.