Children with Mycoplasma pneumoniae antibody-positive cough, considering the cough caused by children with Mycoplasma pneumonia, need to be given general treatment, medication, gammaglobulin, bronchoscopy and other treatments, the use of medication should be in accordance with the doctor’s instructions. Mycoplasma pneumonia in children is characterized by fever and cough, chills, headache and chest tightness, as well as changes in the skin, mucous membrane system and cardiovascular system. 1. General treatment: monitor vital signs, such as body temperature, oxygen saturation, etc., strengthen nutrition, pay attention to water electrolyte supplementation. 2. Drug treatment: preferred macrolides, such as erythromycin, azithromycin, etc., non-macrolide drugs often choose tetracycline such as doxycycline, minocycline, etc., can be applied above 8 years old. If acute onset, rapid development and severe condition, systemic glucocorticoid or inhaled glucocorticoid can be used. 3. Gammaglobulin: combined with autoimmune diseases such as immune hemolytic anemia, central nervous system lesions, immune thrombocytopenic purpura can be considered for application. 4. Pediatric flexible bronchoscopy: it can release the obstruction of the airway, promote pulmonary reopening, and reduce the sequelae. Need to strictly grasp the indications. Children with mycoplasma pneumonia cough, it is recommended to timely diagnosis and treatment, strictly under the guidance of the doctor to use drugs.