Symptoms of triple-negative breast cancer may include painless lumps, localized breast elevation, nipple deviation and “dimple sign”, “orange peel” change of skin, skin ulceration and bleeding. 1. Painless lumps: most of them are early manifestations, which are hard to be detected by patients. 2. Localized breast elevation: the lump is hard, the surface is rough and not smooth, and the boundary with the surrounding tissues is not clear, with the gradual increase of the tumor, it can cause localized elevation of the breast. 3. Nipple deviation and “dimple sign”: when the tumor invades Cooper’s ligament, the ligament will be shortened, which will lead to the depression of the skin on the surface of the tumor, i.e. “dimple sign”, and the adjacent nipple will be shortened due to the invasion of the milk ducts, which will lead the nipple towards the side of the cancer, thus causing the nipple to be pulled to the side of the cancer. The adjacent nipple will be shortened due to the invasion of milk ducts, and the nipple will be pulled to the side of the tumor, making the nipple flat and concave. 4. “Orange peel color change” of skin: when the tumor grows to the extent that the lymphatic vessels are blocked by the cancer cells, it will cause obstruction of lymphatic reflux, resulting in dermal edema, which will lead to “orange peel-like” change of skin. 5. Skin ulceration and bleeding: when advanced cancer cells invade into skin, it can lead to skin ulceration and bleeding. Patients with triple-negative breast cancer should strive for early treatment, actively cooperate with doctors to receive treatment and do not lose confidence.