The treatment of positive urinary bilirubin needs to choose different treatments according to different causes, and common treatments include medication, surgery, etc. Common causes include hemolysis, viral hepatitis and gallstones. 1. There may be hemolysis in the body, increased destruction of red blood cells, so that bilirubin increases, increased bilirubin beyond the liver’s ability to remove, it will be discharged from the urine, resulting in the emergence of urine bilirubin positive. The treatment for this is to treat the cause, if it is autoimmune hemolysis usually choose glucocorticoid treatment, commonly used drugs are prednisone, hydrocortisone and so on. 2. Viral hepatitis may cause the function of liver cells to be impaired, and the clearance of bilirubin will be reduced, and a large amount of bilirubin will be excreted through the kidneys, leading to the emergence of positive urinary bilirubin. The treatment of viral hepatitis is generally causative, and viral hepatitis can be treated with medication, such as antiviral drugs such as vipatavir and sofosbuvir, and hepatoprotective drugs such as polyene phosphatidylcholine and reduced glutathione. 3.may suffer from gallstones, bile duct obstruction, resulting in bilirubin metabolism obstacles, bilirubin excretion from the kidneys, appear urine bilirubin positive. The treatment for gallstones can be medication, commonly used drugs such as ursodeoxycholic acid, but also the option of surgical treatment to remove gallstones. There are many other causes and treatments for urine bilirubin positivity, but the treatment is generally based on the cause of the disease, and after the cause is removed, the symptoms will be relieved. The above medications should be used under medical supervision.