A global survey by the World Health Organization shows that only 5% of people are truly healthy, 20% are suffering from diseases, and 75% are in a sub-healthy state. It is a state between health and disease, with no clinical symptoms or mild symptoms, but with underlying pathological information. The most important manifestation is the chronic fatigue syndrome. Chronic fatigue syndrome (CFS) is a group of systemic syndromes mainly manifested by prolonged extreme fatigue, with non-specific manifestations such as fatigue, hypothermia (or spontaneous fever), sore throat, myalgia, arthralgia, headache, difficulty concentrating, memory loss, sleep disturbance and depression, often accompanied by headache, lymph node enlargement and pressure pain, and various neuropsychiatric symptoms. Fatigue, as a common symptom in TCM clinics, is often described in ancient TCM texts as “tiredness”, “slackness”, “slackness”, “heavy limbs “, “sleepiness and thinness”, “body weight”, “body weight”, “failure to lift the limbs “, “tiredness of the limbs”, “limbs are limp”, “limbs don’t use”, “annoying barium to take H confused end of the province of the province The “weight of the body is a problem”. Zhang Zhongjing’s “lily disease” and “dirty agitation disease” discussed in “The Essentials of the Golden Horoscope”, “dizziness” described in “Jing Yue Quan Shu”, and the “internal injury disease of the spleen and stomach” played by successive generations of doctors. “internal injury of the spleen and stomach”, “depression”, “insomnia”, “forgetfulness”, “deficiency labor”, etc, “The etiology, pathogenesis, symptoms, and even treatment of these diseases have some similarities with CFS.