High urine microalbumin and urine creatinine can be seen in physiological factors, such as strenuous exercise, eating a lot of meat, etc., at this time there is no need for special treatment, pay attention to rest; pathologic factors, such as diabetic nephropathy, renal insufficiency in the early stages of urinary tract infections, etc., at this time according to the specific cause of the targeted treatment. 1. Physiological factors: such as strenuous exercise, eating a lot of meat food, etc., can lead to high urinary microalbumin, urinary creatinine, at this time no special treatment, pay attention to the review can be. 2. Diabetic nephropathy: urine microalbumin and urine creatinine can be elevated, with the progression of the disease, renal insufficiency can occur, at this time, we need to comply with the doctor’s instructions to apply valsartan, Benadryl, dagliflozin and other drugs, pay attention to monitoring changes in indicators to slow down the progress of the disease. 3. Early stage of renal insufficiency: irreversible loss of renal units and renal function caused by progressive development of various renal diseases. Urine microalbumin and urine creatinine can be elevated, at this time need to comply with medical advice oral valsartan and other drugs. 4. Urinary tract infection: in addition to the manifestation of urinary frequency, urinary urgency, urinary pain, there may be urine microalbumin, urine creatinine elevation, at this time the need for active anti-infection treatment, can choose amoxicillin capsule, cefuroxime and other medications, infection control and then review the index of change. The above medication, need to follow the doctor’s instructions, not unauthorized use. Urine microalbumin, urine creatinine is high for many other reasons, it is recommended that patients timely regular hospital consultation, under the guidance of physicians standardized treatment.