There is no such thing as the best clinical treatment for degenerative arthritis of the knee. Degenerative arthritis of the knee can be treated by conservative, drug therapy, intra-articular injection and surgery. 1. Conservative treatment: Degenerative knee arthritis is a sterile inflammation formed by long-term strain and degeneration of joints. In the early stage, most people choose conservative treatment, such as paying attention to rest, keeping warm, avoiding cold, wearing knee pads, hot compresses, baking, massage and other physiotherapy treatments. 2. Medication: If the pain is obvious, oral anti-inflammatory and analgesic drugs such as nimesulide and diclofenac sodium can be taken, as well as oral aminoglucose sulfate to protect the articular cartilage. 3. Intra-articular injection: In the middle stage of arthritis, intra-articular injection of sodium vitrate is also an option. 4. Surgery: For patients with more serious conditions, minimally invasive treatments such as arthroscopy can be used to clean up the joints. For very serious degenerative arthritis, surgery can be chosen, such as artificial knee replacement. If the symptoms of degenerative arthritis of the knee, it is recommended that patients go to the hospital to improve the examination and regular treatment.