Thalassemia genetic screening is necessary. Thalassemia, also known as thalassemia maritima, is the most common single-gene genetic disease, which is inherited by autosomal recessive inheritance. Therefore, some people are actually thalassemia gene carriers even though they do not show corresponding symptoms, so thalassemia gene screening is necessary. There is no special cure for thalassemia, and the heavy type is mostly seen in children, with symptoms such as fatigue, dullness, low fever, poor growth and development, hypogonadism, etc. Therefore, if both husband and wife are screened for the thalassemia gene before pregnancy, they can determine whether their children will carry the thalassemia gene through the probability of inheritance. Therefore, thalassemia gene screening is necessary, especially for couples with family history of the disease or those who are preparing for pregnancy.