The cause and pathogenesis of rheumatoid arthritis is still unclear, and there is still no cure, but early and regular treatment can enable the majority of patients to achieve complete remission and normal life, although it cannot be cured, but on the current treatment methods and strategies can fully achieve the purpose of living with the disease, that is, lifelong concomitant disease. Treatment goals: 1. complete remission (no joint swelling and pain, normal blood sedimentation) 2. low disease activity Treatment features: “combined cycle, immune regulation” New concept, new method Treatment plan: Intensive treatment – is the key Maintenance treatment – is the soul I. Intensive treatment ( Achieve the above goals in the shortest possible time) 1.Non-steroidal anti-inflammatory drugs Meloxicam, Loxone, Aceclofenac, Cilobal, Etoricoxib, etc. Characteristics: It is the basic drug, with anti-inflammatory and analgesic effect, the main side effects are gastrointestinal reactions, and can be discontinued after achieving the goals. 2.Hormones Prednisone, Depo-Provera, methylprednisolone, etc. Features: can quickly eliminate inflammation and analgesia, improve symptoms, cheap but to bear more side effects of drugs, as a bridge treatment is a very good means, but as far as possible short-term use, discontinue as soon as possible. 3, biological agents Ixeprop, prednisolone, Enzyme, classical gram, Xumel and Yamiro; Features: rapid relief, little side effects, is the best choice in treatment at present, but more expensive, some patients may be ineffective. If economic conditions allow, it can be applied for a long time. Second, maintenance therapy (after treatment to maintain long-term clinical remission) 1, DMARDs for remission drugs, the main drugs are methotrexate, leflunomide, cyclophosphamide, mycophenolate, azathioprine, salazosulfapyridine and hydroxychloroquine sulfate, etc. Features: slow onset of action, generally takes three months, need to take long-term, to cycle combined, but can be based on the condition of the up and down step increase or decrease the dosage, some patients can Some patients can stop taking the drug, but long-term follow-up observation is required. 2. Biological agents such as Ixeprop, Qiangk, Enzyme, Classical, Xumel and Yamiro, etc. Features: rapid relief, small side effects, long-term application, if economic conditions allow is the best choice for maintenance treatment, such as a biological agent is not effective, can be converted to another, still effective, but close follow-up to detect infection and other diseases.