For the sake of fetal health, both men and women should undergo detailed pre-conception checkups before preparing for pregnancy. The basic checkups include blood sugar, blood routine, coagulation function and electrocardiogram, etc., to clarify whether there are any unfavorable factors affecting fetal growth and development. For the pre-conception checkups, there are two aspects of checkups for both men and women, and the details are as follows: 1. For women: including general checkups, gynecological checkups, eugenics five items, blood lipids, blood sugar, liver function, kidney function and other aspects. For example, routine gynecological examination to clarify the presence of reproductive organ abnormalities, vaginitis, uterine tumors and other gynecological diseases; tubal lavage examination 3-5 days after menstruation to clarify the presence of tubal blockage; chromosome examination to clarify the presence of family genetic family diseases; vaginal discharge examination to clarify the presence of trichomonas, mycobacteria, mycoplasma, chlamydia infection, etc.; 2. For men: including Male hormone four, surgical examination, liver function and other aspects. For example, we can check men’s semen routine to clarify whether there are factors affecting pregnancy preparation; check male hormone quadruple test to determine whether the hormone level in men is normal; conduct routine blood test to clarify whether there are anemia, bacterial infection, viral infection, leukemia and other blood diseases; check urine routine to clarify whether there are infectious diseases of urinary system, acute and chronic kidney diseases and metabolic disorders related to kidney, etc.