The new 4-treatment is a new treatment for H. pylori infection. Previously, H. pylori eradication treatment was mainly done by 3-treatment. However, according to clinical experience, the eradication rate of H. pylori in 3CT does not reach the effective treatment purpose, and many cases of H. pylori infection treatment failure, so 4CT is adopted. 4CT is based on 3CT with the addition of bismuth, commonly used drugs are bismuth pectin or bismuth potassium citrate. 4CT differs from 3CT in the treatment course, 4CT takes 2 weeks of The efficiency of HP eradication can reach more than 95% with a 2-week treatment regimen. After the eradication of HP, the carbon 13 or carbon 14 breath test can be repeated for 1 month after stopping the drug, and most of them can be effectively eradicated.