Common causes of knee ligament ossification include meniscus injury, osteoarthritis, rheumatoid arthritis, trauma, etc. It can be improved by general treatment, medication and physical therapy. 1. General treatment: It is recommended to avoid strenuous exercise, take sufficient rest and relax the mind to improve the symptoms and slow down the progress of the disease. 2. Drug treatment: When pain occurs, drugs such as ibuprofen can be taken to relieve pain, and drugs such as salicylazosulfapyridine and cyclophosphamide are also recommended to treat the cause of the disease. Due to individual differences and the diversity of causes, the drug is not absolutely the most effective, need to be used under the guidance of a doctor, the emergence of adverse reactions in time to consult a doctor. Drug allergy is prohibited. 3. Physiotherapy: In addition to the above treatments, infrared irradiation, shock wave therapy and functional exercises can also effectively improve the prognosis of the disease. It is recommended that the patients concerned should consult a doctor for timely examination and targeted treatment and management.