Taking levamlodipine benzenesulfonate for a long period of time is not harmful, but it may have some adverse reactions. Adverse reactions and harmful are not the same concept, you can generally say that the drug has adverse reactions but not that it is harmful. Patients generally tolerate levamlodipine benzenesulfonate well. Less common adverse reactions are headache, edema, fatigue, insomnia, nausea, abdominal pain, flushing, palpitations and dizziness. Very rare adverse reactions are pruritus, rash, dyspnea, weakness, muscle cramps and dyspepsia. It is contraindicated in patients who are hypersensitive to dihydropyridine calcium antagonists. Some of the above symptoms may occur if patients take amlodipine benzenesulfonate tablets orally for a long period of time. At this time, they should immediately seek medical attention, and can appropriately reduce the dosage of the drug, and if necessary, switch to other types of antihypertensive drugs for antihypertensive treatment. Drugs should be taken under the guidance of a physician, and should not be blindly used or discontinued without authorization.