Patients who suffer from feet with a sour odor may be related to the lack of breathability of shoes and socks, hyperhidrosis, tinea pedis and other factors, and patients can alleviate the condition through general treatment, medication, surgery and other ways. 1. Breathless shoes and socks: patients should pay attention to foot cleaning, keep feet clean and fresh, wash feet and socks diligently, try to wear shoes and socks with better breathability, and expose them to the sun after cleaning to achieve the effect of sterilization. 2. Hyperhidrosis: Hyperhidrosis patients should pay attention to personal hygiene, can follow the doctor’s instructions to use topical drugs, such as 5% alum solution, 5% tannic acid solution, etc.; systemic drugs, such as bromine, phenobarbital, chlorpromazine, etc. for treatment. For conservative treatment is ineffective patients can be treated by sympathectomy, relieve the situation of sweaty feet, improve foot odor and so on. 3. Tinea pedis: Tinea pedis may also cause the situation of sour feet, patients can follow the doctor’s instructions to use antifungal drugs, such as clotrimazole, naftifine, amorphophine, etc. for treatment, for the appearance of skin lesions or secondary infections can be applied locally 1:5000 potassium permanganate solution or 0.1% levonorgestrel and other medications, to improve the situation of sour feet. It is recommended that patients strictly follow the doctor’s instructions for medication, actively cooperate with the doctor’s treatment, do not share nail clippers, shoes, foot basins, foot wipes and other daily necessities, pay attention to the monitoring of the condition, and once the condition worsens or other adverse reactions occur, it is necessary to seek medical treatment in a timely manner.