After touching chili peppers, it is recommended to use cold water for rinsing, or topical medication to relieve the pain. 1. Use cold water for rinsing: after touching chili peppers feel very hot hands, it is recommended to use cold water for rinsing, can reduce the role of skin microvascular dilation, relieve the pain. Because capsaicin is not soluble in water, running water rinse is not able to wash away the capsaicin into the skin. However, capsaicin is soluble in alcohol or acetic acid, so white wine or vinegar can be used to rub hands to remove capsaicin as soon as possible. 2. Topical medication to relieve: after using cold water to rinse and still do not see any improvement, it is recommended that under the guidance of a doctor, appropriate topical glycerine lotion to carry out treatment can play a role in relieving the pain. It is recommended to wear protective gloves when cutting chili peppers to reduce the contact between skin and capsaicin.