Amoxicillin can cure diarrhea but it is not recommended because it does not achieve the desired effect. Diarrhea is usually caused by E. coli or other gram-negative bacteria, and amoxicillin mainly targets gram-positive bacteria, so amoxicillin does not achieve the desired effect in treating diarrhea. Amoxicillin belongs to the penicillin class of drugs, it is easy to cause allergies, it is recommended that patients use caution, generally used to treat diarrhea or intestinal infection drugs preferred quinolone antibiotics, that is, norfloxacin or ofloxacin, etc.. But before using antibiotics must be perfected related tests, such as stool routine, rotavirus, stool culture, blood routine, blood biochemistry and other related tests. If it is clear that the infection is bacterial and there are indications for antibiotic use, then antibiotic treatment can be used.