Beta thalassemia is not dominantly inherited but autosomal recessive.
Thalassemia is a chromosomal recessive hereditary blood disorder, mainly because of the imbalance between the synthesis of α-bead protein peptide chain and β-bead protein peptide chain synthesis of hemoglobin, so it leads to the abnormal structure of hemoglobin, and the life span of the red blood cells that contain these abnormal hemoglobin will become shorter, and even be destroyed by the human body’s liver and spleen in advance, which will finally lead to the manifestation of anemia and other manifestations.
Beta thalassemia is a group of hemoglobinopathies in which the synthesis of the peptide chain of beta bead protein is partially or completely inhibited. Since the disease is autosomal recessive, its occurrence is not related to gender, and men and women have equal chances of developing the disease, and the causative gene only develops in a pure state.
If both parents of the patient are phenotypically normal, but both are carriers of the disease-causing gene, the chance of giving birth to a child with anemia is one in four.
It is recommended that both spouses should go to the local maternal and child health center or regular hospitals for consultation before preparing for pregnancy, and genetic and hematological tests should be performed in the early and middle stages of pregnancy. Specific disease diagnosis and treatment should be carried out under the guidance of physicians.