Take ibuprofen for 4 to 6 hours before taking pediatric aminoglutethimide, and the medication should be taken as prescribed by your doctor. Ibuprofen is used for fever and mild to moderate aches and pains caused by colds. Adverse reactions to this product can be seen as stomach upset, abdominal pain, nausea, vomiting, rash, facial edema. This product is contraindicated in people with peptic ulcers, allergy to the components of the product, pregnant and lactating women. The use of ibuprofen requires an interval of 4-6 hours before repeating the drug once, and should not be used more than 4 times in 24 hours. Pediatric aminoglutethimide is used to relieve fever and other symptoms caused by colds. It is contraindicated in severe hepatic and renal insufficiency, and under 1 year of age. Adverse reactions include mild dizziness, fatigue and nausea. The drug contains acetaminophen in its composition, and ibuprofen are both antipyretic and analgesic drugs. Both are used as antipyretic drugs with an interval of 4 to 6 hours. Specific medication should be used reasonably under the guidance of a doctor.