Ozone therapy is a kind of therapy with anti-inflammatory, analgesic and promoting tissue regeneration, etc. Currently, it is widely used in pain, gynecology, stomatology, etc. In orthopedics, it is mainly used for treating osteoarthropathy as well as herniated disc and other diseases. Lumbar intervertebral disc herniation is mainly due to the herniation compression of nerves and cause pain, ozone injection in the intervertebral disc can relieve nerve root compression, improve the surrounding blood microcirculation, outside the intervertebral disc can increase the oxygen supply, inhibit the release of inflammatory factors, etc., to play the role of anti-inflammatory and analgesic. Lumbar intervertebral disc herniation ozone injection is a minimally invasive treatment, there are certain indications, namely, lumbar intervertebral disc herniation should not be too large, if the herniation is too large, you need to choose other minimally invasive surgery or open surgery, and the effect of injecting ozone is relatively small if the nerve root edema where the compression is obvious. The appearance of lumbar disc herniation, it is recommended that patients seek medical treatment in a timely manner, under the guidance of the doctor to receive regular treatment, so as not to delay the condition.