In daily clinics, patients often ask: “Can I still get pregnant if I have an STD, and will it affect my child?” This is an issue of great concern to women, because most STDs occur in men and women of childbearing age, and pregnancy and childbirth are things that married women are bound to encounter, so it is necessary to talk about the relationship between STDs and pregnancy. A, syphilis and pregnancy In recent years, for various reasons, the occurrence and prevalence of syphilis is on the rise year by year. There is a report that the incidence of syphilis in China rose by 18.8% annually between 2001 and 2007. All cities are on the rise, and Tianjin is no exception. The incidence of syphilis in Tianjin increased year by year from 2001 to 2006, with an average annual increase of 42.66% (100-140-196). The incidence of syphilis has risen much faster than other sexually transmitted diseases such as gonorrhea, condyloma acuminata, and non-gonococcal urethritis. In April 2012, the Ministry of Health counted the national syphilis epidemic, and 38,504 cases of syphilis were reported nationwide, ranking third in all category B infectious diseases (2 in category A and 26 in category B, reported monthly in all medical units, the top two being viral hepatitis and tuberculosis), an increase of 2.5% over the same period the previous year, with a male to female sex ratio of 0.9:1. My graduate students conducted a five-year study of our department from 2006-2010 We have also experienced that there are more and more female syphilis patients in our clinic. What are the consequences for the child if a woman with syphilis becomes pregnant? Women with early syphilis (including stage 1 and stage 2 syphilis) who become pregnant without regular treatment will affect the fetus 100% of the time, resulting in congenital syphilis (fetal syphilis). Another 50% of these women will have a miscarriage, premature birth, or fetal death in utero. Seventy percent of children born to women with untreated latent syphilis will show signs of congenital syphilis. Previously, the premarital screening program routinely screened for syphilis, and if so, the marriage license was not issued first and the child went to a hospital for formal treatment. Now premarital screening is voluntary, part of the syphilis is no symptoms (latent syphilis, and over the years the incidence of latent syphilis is increasing, accounting for more than half), that is, two people are married, one or two of them suffer from syphilis, but do not know, until the woman is pregnant, to the hospital to establish a pregnancy file, a laboratory test was found to have syphilis. If it is detected early in pregnancy is good, seize the time to treat, most of them can block the transmission of syphilis, not infected to the fetus; but some pregnant women in the early stage also do not go to the hospital, and some hospitals do not do syphilis screening for pregnant women, so that the detection of this asymptomatic syphilis, some pregnant women until late pregnancy or even before the delivery of blood tests to detect syphilis, so that the chances of having a congenital syphilis fetus will be greatly increased. The chance of having a fetus with congenital syphilis is greatly increased. I saw a case last week of a 39-year-old woman who underwent IVF and ended up with twin boys, and naturally the couple was very happy. The mother had never been tested for syphilis from before she got married to after she got pregnant, and she did not have any symptoms of syphilis, but she was admitted to a large hospital before delivery, and then she was tested routinely and found to have syphilis at once, but it was too late to treat them, so she gave birth to the twins by C-section. The neonatologist was very nervous and called us to request a consultation. Imagine how the couple would feel when they found out the result. Such cases are not uncommon these days. Nowadays, congenital syphilis has become the most prevalent sexually transmitted disease in children, so here we also remind our obstetricians and pediatricians to pay great attention to gestational syphilis and congenital syphilis. Generally speaking, a woman with syphilis has a high chance of transmitting it to an adult male within two years, but after two years, the infectiousness decreases greatly, but an untreated woman with syphilis can transmit it to her fetus for at least five years, but the longer the disease lasts, the less likely it is to be transmitted to the fetus. Therefore, women with syphilis must be cured of syphilis before pregnancy, even if the syphilis seropositivity has not completely turned negative, under the guidance of the doctor, the required treatment in sufficient quantity before pregnancy and children. Second, gonorrhea and pregnancy gonorrhea used to be the most common type of STD, due to the relatively simple and fast treatment, early treatment cure rate is very high, relatively good treatment, so the control is better, the incidence of these years in the reduction. According to the Ministry of Health, 7,203 cases of gonorrhea were reported nationwide in April 2012, down 11.6% from the same period last year, ranking 5th in category B infectious diseases. The most important characteristic of gonorrhea-infected women is that after being infected by gonococcus, more than half of the patients do not show obvious clinical symptoms, while pregnant women with gonorrhea have more serious symptoms than those who are not pregnant, and treatment is more difficult. When gonococcal cervicitis is contracted early in pregnancy and abortion is performed without cure, the incidence of postoperative endometritis is three times higher than that of women without gonorrhea, and there is an increased chance of causing gonococcal tubitis. In addition, disseminated gonorrhea infections, which are more likely to be seen in pregnant women than in non-pregnant women, present with fever, rash, arthritis, endocarditis, myocarditis, perihepatitis, meningitis, and sepsis. Gonorrhea infection during labor is associated with premature rupture of the amniotic membrane, prolonged rupture of the membrane, and chorioamnionitis. When gonorrhea is contracted late in pregnancy, the fetus passes through the birth canal during birth and gonorrhea infects the eyes of the newborn, causing neonatal gonorrheal ophthalmia. Therefore, women who have gonorrhea must also be cured of gonorrhea before pregnancy. Third, chlamydia and mycoplasma infections and pregnancy Chlamydia and mycoplasma infections currently account for the first place in STD clinics and are extremely closely related to pregnancy. Prenatal chlamydia infection can cause amnionitis, postpartum endometritis, and post-abortion tubal infection. If a pregnant woman with chlamydia is delivered vaginally, 60-70% of newborns have the possibility of being infected, about 25%-50% have conjunctivitis, and 10%-20% have chlamydial pneumonia. Mycoplasma infections can cause inflammation of the uterus and adnexa. Women with human mycoplasma infections in the reproductive tract have a higher risk of spontaneous abortion than those without mycoplasma. Usually human mycoplasma and endometritis are associated with postpartum fever. Mycoplasma decidua and amniotic fluid infection, chorioamnionitis, low birth weight babies, and preterm birth are related. Fourth, genital herpes and pregnancy Genital herpes is caused by herpes simplex virus infection. Herpes simplex virus infection in pregnancy is associated with spontaneous abortion and premature birth. Pregnant women infected with herpes simplex virus during the first three months of pregnancy often give birth to babies with congenital malformations, such as microcephaly, microphthalmia, abnormal retinal development and brain calcification. Severe neonatal herpes simplex virus infections can even be life-threatening. The actual fact is that not only are warts harmful to the pregnant woman herself, but the fetus, if delivered through the birth canal, will be infected with HPV and develop pharyngeal warts. The above shows that STDs are closely related to pregnancy, so it is important to remind women who are suspected of having STDs or have STDs to undergo formal examination or formal treatment before becoming pregnant to ensure the physical and mental health of the next generation.