Cirrhosis, hepatocellular carcinoma and other diseases leading to liver failure may result in upper gastrointestinal hemorrhage, hepatic encephalopathy, hepatorenal syndrome and even life-threatening conditions. Liver cirrhosis advanced stage, liver cancer and other diseases serious state will lead to liver failure, due to the liver portal vein is an important blood reflux channel of gastrointestinal digestive tract, when liver cirrhosis and liver cancer occurs this pathway is blocked, resulting in portal hypertension, varicose veins of the lower esophagus, upper gastrointestinal hemorrhage occurs after swallowing harder food, and in serious cases, shock occurs or even death. In addition, liver as an important detoxification and metabolism organ of the whole body, the function of processing of blood ammonia and other substances is seriously insufficient after liver failure, which in turn leads to hepatic encephalopathy coma or even death; due to the influence of the blood reflux and blood supply of the whole body, kidneys are more sensitive to ischemia, and renal dysfunction will occur in a very short period of time. It is recommended that patients with hepatitis, liver cirrhosis, liver cancer and other diseases should consult a doctor in time, improve the abdominal ultrasound liver function and other auxiliary examinations, and under the guidance of the doctor’s advice, carry out the corresponding drug or surgical treatment.