Plaque in the neck vessels cannot usually be eliminated and can only be stabilized by medication and lifestyle modifications. Drug therapy is mainly statin therapy, such as atorvastatin, etc. Statins can play a role in stabilizing plaque as much as possible, delaying its progression or the emergence of surface rupture secondary to thrombosis and other adverse events. It has been suggested that statin drugs combined with PCSK9 inhibitors keep LDL at very low levels and may even reverse plaque. Antiplatelet agents such as aspirin can also help prevent thrombotic complications from plaque instability. Patients with cervical plaques should actively control the above risk factors, eat a proper diet and exercise moderately to slow down plaque development. Atherosclerotic plaques in neck vessels cannot be eliminated, but they can be treated by controlling risk factors such as hypertension, hyperlipidemia, hyperglycemia, abstaining from smoking and alcohol, exercising moderately, and combining with standardized medication.