There are many reasons for mouth numbness after drinking alcohol, and the common reasons are as follows: 1, due to allergy: drinking alcohol triggers alcohol allergy, and some patients manifested as numbness of the mouth; 2, alcohol poisoning: the phenomenon of alcohol poisoning, so that the local tissues are damaged, which in turn appears as numbness of the mouth, hand numbness symptoms; 3, acetaldehyde paralysis: the patient may be drinking alcohol, alcohol accumulation in the body and the metabolism of ethanol into acetaldehyde, which is irritating to the surrounding tissues and paralyzing effect. Electrolyte disorders: patients may vomit after drinking alcohol, resulting in electrolyte and fluid abnormalities in the body, low potassium, low calcium, which in turn manifested as numbness of the mouth; 5, primary diseases: patients may have some primary diseases, such as cerebrovascular, cerebral infarction, cerebral hemorrhage, alcohol consumption triggered the attack of the underlying disease, which led to the symptoms of numbness of the mouth.