Chest pain when touched is usually due to inflammation of the muscle and nerve tissue at the site of pain, or trauma and tumor lesions, touching can cause changes in tissue or muscle tension at the site of the lesion and pain occurs. Commonly seen in chest wall trauma, chest wall neurological lesions, female breast disease, pleurisy and so on. 1. Chest wall trauma: soft tissue injury of chest wall or rib fracture, gently touching the injured part can cause chest wall pain. 2. Neurological lesions of the chest wall: chondromalacia and intercostal neuritis can cause and aggravate chest pain when touching the area between the ribs at the onset of the disease. 3. Female breast disease: female breast hyperplasia, acute mastitis and breast cancer can also cause pain when touching. 4. Pleurisy: caused by bacterial, fungal, viral infection of the pleura or cancer invasion, manifested by coughing, coughing up phlegm, chest tightness, dyspnea, which may lead to chest pain when touching. It is recommended to go to the hospital as soon as possible for further diagnosis and treatment if your chest hurts when you touch it.