LDL cholesterol 3.87mmol/L is serious if combined with multiple cardiovascular disease risk factors, not serious in patients with elevated lipids alone. The normal value for LDL cholesterol is 0-3.37 mmol/L, and 3.87 mmol/L exceeds the normal value. Patients with elevated LDL are evaluated for cardiovascular risk factors, which include smoking, hypertension, and family history of early-onset cardiovascular disease. Patients with elevated LDL alone, if not combined with other cardiovascular and cerebrovascular risk factors, the condition is not serious and does not require special treatment, usually pay attention to low-salt and low-fat diet. LDL 3.87mmol/L if combined with a variety of risk factors, belonging to high-risk patients, the risk of acute cardiovascular and cerebrovascular disease significantly increased, the condition is relatively serious, need to take oral statin medication, such as atorvastatin, to control the level of LDL to <1.8mmol/L. Patients with elevated LDL should be evaluated for risk and a specific treatment plan should be developed under the supervision of a physician.